Type: | Family | Name: | Probable phospholipid-transporting ATPase VA |
Description: | Probable phospholipid-transporting ATPase VA (also known as ATP10A or ATP10C) belongs to the IV subfamily of the P-type ATPases (P4-ATPase) family. P4-ATPases are phospholipid flippases that translocate phospholipids from the exoplasmic (lumenal) to the cytoplasmic leaflet of lipid bilayers. ATP10C requires CDC50A for its exit from the endoplasmic reticulum (ER) and final subcellular localisation []. ATP10C has been linked to diseases such as Angelman syndrome [] and type 2 diabetes []. | Short Name: | ATP10A/ATP10C |