| Type: | Conserved_site | Name: | Oxysterol-binding protein, conserved site |
| Description: | A number of eukaryotic proteins that seem to be involved with sterol synthesis and/or its regulation have been found [] to be evolutionary related. These include mammalian oxysterol-binding protein(OSBP), a protein of about 800 amino-acid residues that binds a variety of oxysterols (oxygenated derivatives of cholesterol); yeast OSH1, a protein of 859 residues that also plays a role in ergosterol synthesis; yeastproteins HES1 and KES1, highly related proteins of 434 residues that seem to play a role in ergosterol synthesis; and yeast hypothetical proteins YHR001w, YHR073w and YKR003w.This entry represents a sequence region in these proteins that contains a conserved pentapetide. | Short Name: | Oxysterol-bd_CS |
