Protein Domain : IPR029463

Type:  Domain Name:  Lysine-specific metallo-endopeptidase
Description:  This is the catalytic domain of aspzincins, a group of lysine-specific metallo-endopeptidases in the MEROPS M35 family. They exhibit the following active-site architecture: the active site is composed of two helices and a loop region and includes the HExxH and GTxDxxYG motifs. In protein , His117, His121 and Asp130 coordinate to the catalytic zinc ligands. An electrostatically negative region composed of Asp154 and Glu157 attracts a positively charged Lys side chain of a substrate in a specific manner []. Short Name:  Lys_MEP
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0 Child Features

0 Contains

1 Cross References

Identifier
PF14521

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0004222 IPR029463

1 Ontology Annotations

GO Term Gene Name
GO:0004222 IPR029463

1 Parent Features

DB identifier Type Name
IPR024079 Domain Metallopeptidase, catalytic domain

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Medtr1169s0010.1 A0A072TDF1 PAC:31101031 Medicago truncatula 486  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11223512