Protein Domain : IPR010504

Type:  Domain Name:  Arfaptin homology (AH) domain
Description:  The arfaptin homology (AH) domain is a protein domain found in a range of proteins, including arfaptins, protein kinase C-binding protein PICK1 [] and mammalian 69 kDa islet cell autoantigen (ICA69) []. The AH domain of arfaptin has been shown to dimerise and to bind Arf and Rho family GTPases [, ], including ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature secretory granules.The AH domain consists of three alpha-helices arranged as an extended antiparallel alpha-helical bundle. Two arfaptin AH domains associate to form a highly elongated, crescent-shaped dimer [, ]. Short Name:  AH_dom
Paste the following link

1 Child Features

DB identifier Type Name
IPR004148 Domain BAR domain

0 Contains

3 Cross Referencess

Identifier
PF06456
PS50870
SM01015

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0019904 IPR010504

1 Ontology Annotations

GO Term Gene Name
GO:0019904 IPR010504

1 Parent Features

DB identifier Type Name
IPR027267 Domain Arfaptin homology (AH) domain/BAR domain

19 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Cre06.g281050.t1.2 A8J216 PAC:30778806 Chlamydomonas reinhardtii 410  
Sphfalx0038s0051.1.p PAC:32603380 Sphagnum fallax 835  
Pp3c7_960V3.1.p A0A2K1K9T7 PAC:32923221 Physcomitrium patens 817  
Pp3c7_960V3.2.p A0A2K1K9T7 PAC:32923222 Physcomitrium patens 817  
Pp3c11_24570V3.2.p PAC:32956643 Physcomitrium patens 816  
Pp3c11_24570V3.1.p A0A2K1JW46 PAC:32956642 Physcomitrium patens 820  
Mapoly0051s0019.1.p A0A2R6WX01 PAC:33021610 Marchantia polymorpha 410  
Pavir.7KG268400.2.p PAC:37684308 Panicum virgatum 329  
Pavir.7KG268400.1.p PAC:37684307 Panicum virgatum 366  
Pavir.7NG264600.1.p PAC:37618803 Panicum virgatum 366  
PhHAL.7G228700.1.p PAC:40431360 Panicum hallii HAL 367  
Pavir.7KG268400.1.p PAC:41575218 Panicum virgatum 366  
Pavir.7NG264600.1.p PAC:41626039 Panicum virgatum 366  
Pavir.7NG264600.3.p PAC:41626041 Panicum virgatum 333  
Pavir.7NG264600.4.p PAC:41626042 Panicum virgatum 244  
Pavir.7NG264600.2.p PAC:41626040 Panicum virgatum 364  
PhHAL.7G228700.1.p PAC:45973434 Panicum hallii HAL 367  
Ceric.06G061300.3.p PAC:50620336 Ceratopteris richardii 406  
Ceric.06G061300.1.p PAC:50620335 Ceratopteris richardii 406  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11346801
            12682071
            10623590
            11696355