Protein Domain : IPR003410

Type:  Domain Name:  HYR domain
Description:  The HYR (HYalin Repeat) domain is an extracellular domain of about 80-100 amino acids. It has been named after the hyalin protein, which is composedexclusively of repeats of this domain. The HYR domain is found in several eukaryotic proteins, either in multiple copies as in hyalin or in associationwith other domains like the CCP (sushi) domain, the Von Willebrand factor type A (VWA) domain, the EGF-like domain, the calcium-binding EGF-like domain, the pentraxin domain, the CUB domain, the LDL-receptor class A domain, the C-type lectin domain or the discoidin domain. As the HYR domains of hyalin have been shown to contain the ligand for the hyalin cell surface receptor, the HYR domain can also be expected to play a direct role in cellular adhesion in other proteins in which it is present [].Secondary structure predictions of the HYR domain indicate an all-beta fold including seven beta-strands. The HYR domain shares clear sequencesimilarities limited to the C-terminal region with the Fn3 and PKD domains and is believed to belong to the immunoglobulin-like fold []. Short Name:  HYR_dom

0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF02494
PS50825

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Cre04.g223650.t1.1 A0A2K3DUE7 PAC:30791554 Chlamydomonas reinhardtii 1321  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10933504