Protein Domain : IPR007111

Type:  Domain Name:  NACHT nucleoside triphosphatase
Description:  The NACHT domain is a 300 to 400 residue predicted nucleoside triphosphatase (NTPase) domain, which is found in animal, fungal and bacterial proteins. The NACHT domain has been named after NAIP, CIITA, HET-E and TP1. It is found in association with other domains, such as the CARD domain (), the DAPIN domain (), the HEAT repeat (), the WD repeat (), the leucine-rich repeat (LRR) or the BIR repeat () [].The NACHT domain consists of seven distinct conserved motifs, including the ATP/GTPase specific P-loop, the Mg(2+)-binding site (Walker A and B motifs, respectively) and five more specific motifs. The unique features of the NACHT domain include the prevalence of 'tiny' residues(glycine, alanine or serine) directly C-terminal of the Mg(2+)-coordinating aspartate in the Walker B motif, in place of a second acidic residue prevalent in other NTPases. A second acidic residue is typically found in the NACHT-containing proteins two positions downstream. Furthermore, the distal motif VII contains a conserved pattern of polar, aromatic and hydrophobic residues that is not seen in any other NTPase family []. Short Name:  NACHT_NTPase
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0 Child Features

0 Contains

1 Cross References

Identifier
PS50837

1 Found In

DB identifier Type Name
IPR008095 Family MHC class II transactivator

0 GO Annotation

0 Ontology Annotations

0 Parent Features

10 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Cre10.g423600.t1.1 A0A2K3D9D5 PAC:30789739 Chlamydomonas reinhardtii 2169  
Cre17.g723450.t1.1 A0A2K3CQG1 PAC:30782721 Chlamydomonas reinhardtii 1807  
Cre17.g723450.t2.1 A0A2K3CQG1 PAC:30782722 Chlamydomonas reinhardtii 1807  
Medtr1g090680.1 A0A072VZ22 PAC:31097994 Medicago truncatula 1486  
Dusal.0048s00029.1.p PAC:33189474 Dunaliella salina 127  
arahy.Tifrunner.gnm1.ann1.H49T8T.1 PAC:42605876 Arachis hypogaea 3159  
arahy.Tifrunner.gnm1.ann1.H49T8T.3 PAC:42605877 Arachis hypogaea 3159  
CiLak.15G161500.1.p PAC:44265671 Carya illinoinensis Lakota 464  
CiPaw.15G178300.1.p PAC:45815343 Carya illinoinensis Pawnee 873  
Urofu.1G080900.1.p PAC:50119449 Urochloa fusca 509  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10782090