3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003700 | IPR001766 |
| GO:0043565 | IPR001766 |
| GO:0006355 | IPR001766 |
1 Parent Features
| DB identifier | Type | Name |
|---|---|---|
| IPR011991 | Domain | Winged helix-turn-helix DNA-binding domain |
| Type: | Domain | Name: | Fork head domain |
| Description: | The fork head domain is a conserved DNA-binding domain (also known as a "winged helix") of about 100 amino-acid residues.Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors []. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiaeHCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [, , ].The fork head domain binds B-DNA as a monomer [], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis []. | Short Name: | Fork_head_dom |
| GO Term | Gene Name |
|---|---|
| GO:0003700 | IPR001766 |
| GO:0043565 | IPR001766 |
| GO:0006355 | IPR001766 |
| DB identifier | Type | Name |
|---|---|---|
| IPR011991 | Domain | Winged helix-turn-helix DNA-binding domain |
