Protein Domain : IPR014143

Type:  Domain Name:  DNA ligase D
Description:  Members of this entry are DNA ligases involved in the repair of DNA double-stranded breaks by non-homologous end joining (NheJ). The system of the bacterial Ku protein () plus this DNA ligase is seen in about 20% of bacterial genomes to date and at least one archaeon (Archeoglobus fulgidus). This entry describes a central and C-terminal domain. These two domains may be permuted, as in genus Mycobacterium, or divided into tandem ORFs. An additional N-terminal 3 -phosphoesterase (PE) domain () is present in some members of this ligase. Most examples of genes for this ligase are adjacent to the gene for Ku. Short Name:  NHEJ_ligase_prk
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0 Child Features

4 Contains

DB identifier Type Name
IPR012310 Domain DNA ligase, ATP-dependent, central
IPR012309 Domain DNA ligase, ATP-dependent, C-terminal
IPR014146 Domain DNA ligase D, ligase domain
IPR014145 Domain DNA ligase D, polymerase domain

1 Cross References

Identifier
TIGR02776

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
27644.m000028 B9TB64 PAC:16798885 Ricinus communis 841  

0 Publications