Protein Domain : IPR000847

Type:  Domain Name:  Transcription regulator HTH, LysR
Description:  Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI [, , , , ]. The majority of these proteins appear to be transcription activatorsand most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini. Short Name:  Tscrpt_reg_HTH_LysR
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1 Child Features

DB identifier Type Name
IPR003725 Domain Molybdenum-binding protein, N-terminal

0 Contains

3 Cross Referencess

Identifier
PF00126
PR00039
PS50931

6 Found Ins

DB identifier Type Name
IPR017724 Family Aminoethylphosphonate utilisation-associated transcription regulator, LysR-type
IPR012787 Family Pca transcription factor PcaQ
IPR011781 Family D-serine deaminase transcriptional activator
IPR017685 Family HTH-type transcriptional regulator ArgP
IPR017786 Family Transcription factor, choline sulphate-utilisation, putative
IPR020890 Family Transcription regulator HTH, HdfR

2 GO Annotations

GO Term Gene Name
GO:0003700 IPR000847
GO:0006355 IPR000847

2 Ontology Annotations

GO Term Gene Name
GO:0003700 IPR000847
GO:0006355 IPR000847

1 Parent Features

DB identifier Type Name
IPR011991 Domain Winged helix-turn-helix DNA-binding domain

205 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
31047.m000026 B9TF39 PAC:16824771 Ricinus communis 155  
31073.m000022 B9TI09 PAC:16824787 Ricinus communis 300  
31092.m000020 B9TDJ5 PAC:16824805 Ricinus communis 311  
31641.m000031 B9TER2 PAC:16825136 Ricinus communis 279  
32388.m000024 B9TD88 PAC:16825417 Ricinus communis 301  
32749.m000024 B9TDR3 PAC:16825538 Ricinus communis 301  
33005.m000039 B9TCX5 PAC:16825649 Ricinus communis 298  
33544.m000026 B9TIA2 PAC:16825896 Ricinus communis 187  
33454.m000028 PAC:16825847 Ricinus communis 223  
35235.m000023 B9TD41 PAC:16826525 Ricinus communis 302  
35013.m000028 B9TJC3 PAC:16826452 Ricinus communis 192  
36032.m000018 B9TFN5 PAC:16826850 Ricinus communis 294  
45358.m000013 B9TPA8 PAC:16827796 Ricinus communis 258  
49437.m000026 B9TLP6 PAC:16828169 Ricinus communis 172  
52469.m000024 B9TLJ3 PAC:16828522 Ricinus communis 182  
54100.m000029 B9TIQ3 PAC:16828677 Ricinus communis 160  
55526.m000024 B9TN66 PAC:16828820 Ricinus communis 60  
56923.m000023 PAC:16828992 Ricinus communis 140  
27859.m000068 B9TA83 PAC:16799347 Ricinus communis 311  
27571.m000057 B9TBL4 PAC:16798728 Ricinus communis 289  
27442.m000046 B9TBP2 PAC:16798326 Ricinus communis 298  
27431.m000215 B9T8A6 PAC:16798290 Ricinus communis 319  
27391.m000118 B9T7F2 PAC:16798207 Ricinus communis 294  
29031.m000061 B9T8X5 PAC:16802193 Ricinus communis 296  
27472.m000313 B9T7I5 PAC:16798463 Ricinus communis 606  
29164.m000040 B9TBE6 PAC:16802380 Ricinus communis 215  
11790 I0Z6V1 PAC:27393514 Coccomyxa subellipsoidea C-169 345  
Araha.11756s0285.1.p PAC:28856499 Arabidopsis halleri 301  
Medtr1781s0010.1 A0A072TCA0 PAC:31092046 Medicago truncatula 105  
Medtr0803s0010.1 A0A072TDT4 PAC:31115422 Medicago truncatula 320  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1907267
            1592818
            1840615
            3413113
            2034653