Protein Domain : IPR000483

Type:  Domain Name:  Cysteine-rich flanking region, C-terminal
Description:  Leucine-rich repeats (LRR, see ) consist of 2-45 motifs of 20-30 amino acids in length that generally folds into an arc or horseshoe shape []. LRRs occur in proteins ranging from viruses to eukaryotes, and appear to provide a structural framework for the formation of protein-protein interactions []. Proteins containing LRRs include tyrosine kinase receptors, cell-adhesion molecules, virulence factors, and extracellular matrix-binding glycoproteins, and are involved in a variety of biological processes, including signal transduction, cell adhesion, DNA repair, recombination, transcription, RNA processing, disease resistance, apoptosis, and the immune response.LRRs are often flanked by cysteine-rich domains: an N-terminal LRR domain () and a C-terminal LRR domain. This entry represents the C-terminal LRR domain. Short Name:  Cys-rich_flank_reg_C
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF01463
SM00082

7 Found Ins

DB identifier Type Name
IPR000434 Family Polycystic kidney disease type 1 protein
IPR020461 Family Tyrosine-protein kinase, neurotrophic receptor, type 1
IPR020446 Family Tyrosine-protein kinase, neurotrophic receptor, type 3
IPR020455 Family Tyrosine-protein kinase, neurotrophic receptor, type 2
IPR020777 Family Tyrosine-protein kinase, neurotrophic receptor
IPR017241 Family Toll-like receptor
IPR006228 Domain Polycystin cation channel

0 GO Annotation

0 Ontology Annotations

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Bobra.0036s0013.1.p PAC:40722359 Botryococcus braunii 166  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11751054
            14747988