Protein Domain : IPR004365

Type:  Domain Name:  OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
Description:  The OB-fold (oligonucleotide/oligosaccharide-binding fold) is found in all three kingdoms and its common architecture presents a binding face that has adapted to bind different ligands. The OB-fold is a five/six-stranded closed beta-barrel formed by 70-80 amino acid residues. The strands are connected by loops of varying length which form the functional appendages of the protein. The majority of OB-fold proteins use the same face for ligand binding or as an active site. Different OB-fold proteins use this 'fold-related binding face' to, variously, bind oligosaccharides, oligonucleotides, proteins, metal ions and catalytic substrates. This entry contains OB-fold domains that bind to nucleic acids []. It includes the anti-codon binding domain of lysyl, aspartyl, and asparaginyl-tRNA synthetases (See ). Aminoacyl-tRNA synthetases catalyse the addition of an amino acid to the appropriate tRNA molecule . This domain is found in RecG helicase involved in DNA repair. Replication factor A is a heterotrimeric complex, that contains a subunit in this family [, ]. This domain is also found at the C terminus of bacterial DNA polymerase III alpha chain. Short Name:  NA-bd_OB_tRNA

0 Child Features

0 Contains

1 Cross References


12 Found Ins

DB identifier Type Name
IPR002313 Family Lysine-tRNA ligase, class II
IPR002312 Family Aspartyl/Asparaginyl-tRNA synthetase, class IIb
IPR004523 Family Aspartyl-tRNA synthetase, archaeal-type
IPR004524 Family Aspartate-tRNA ligase, bacterial/mitochondrial-type
IPR004591 Family Replication factor A protein 1
IPR014646 Family Replication factor A protein 2
IPR011149 Family DNA polymerase II small subunit, archaeal
IPR006308 Family DNA polymerase III, alpha subunit, Gram-positive type
IPR020873 Family 3'-5' exoribonuclease YhaM
IPR014647 Family CST complex subunit Stn1
IPR016798 Family Uncharacterised conserved protein UCP021980, OB-fold
IPR016499 Family Nucleic acid binding protein, Rv2694c, predicted

1 GO Annotation

GO Term Gene Name Organism
GO:0003676 IPR004365

1 Parent Features

DB identifier Type Name
IPR012340 Domain Nucleic acid-binding, OB-fold

1185 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
79851 D8QXQ7 PAC:15405174 Selaginella moellendorffii 485  
84215 D8R3T7 PAC:15415533 Selaginella moellendorffii 521  
272117 D8T3M2 PAC:15401427 Selaginella moellendorffii 536  
269089 D8SRZ7 PAC:15414224 Selaginella moellendorffii 108  
92995 D8RG18 PAC:15422242 Selaginella moellendorffii 563  
418417 D8S5M5 PAC:15406633 Selaginella moellendorffii 531  
89304 D8RAZ5 PAC:15408428 Selaginella moellendorffii 636  
440021 D8R9G7 PAC:15401840 Selaginella moellendorffii 279  
441216 D8RHE0 PAC:15406242 Selaginella moellendorffii 815  
evm.model.supercontig_119.38 PAC:16406554 Carica papaya 567  
evm.model.supercontig_1312.2 PAC:16408096 Carica papaya 153  
evm.model.supercontig_137.10 PAC:16408398 Carica papaya 543  
evm.model.supercontig_28.78 PAC:16415976 Carica papaya 644  
evm.model.supercontig_37.195 PAC:16418653 Carica papaya 544  
evm.model.supercontig_41.65 J7GKA8 PAC:16419597 Carica papaya 154  
evm.model.supercontig_78.58 PAC:16426236 Carica papaya 572  
evm.model.supercontig_95.40 PAC:16428881 Carica papaya 556  
evm.model.supercontig_1086.1 PAC:16405515 Carica papaya 620  
28226.m000838 B9SPP8 PAC:16800373 Ricinus communis 242  
28842.m000944 B9SBP3 PAC:16801832 Ricinus communis 585  
29428.m000317 B9SY11 PAC:16802834 Ricinus communis 607  
29703.m001484 B9SFH6 PAC:16806180 Ricinus communis 166  
29827.m002600 B9S1L9 PAC:16810032 Ricinus communis 901  
29912.m005276 B9RK18 PAC:16813155 Ricinus communis 670  
29912.m005418 B9RKD2 PAC:16813295 Ricinus communis 155  
30099.m001677 B9S7X4 PAC:16817698 Ricinus communis 668  
30138.m003969 B9RLN2 PAC:16819335 Ricinus communis 622  
Cucsa.152710.1 A0A0A0L1N3 PAC:16964578 Cucumis sativus 603  
Cucsa.168320.1 A0A0A0LNV0 PAC:16966319 Cucumis sativus 168  
Cucsa.198280.1 A0A0A0LSG2 PAC:16968570 Cucumis sativus 623  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID