Protein Domain : IPR009060

Type:  Domain Name:  UBA-like
Description:  UBA domains are a commonly occurring sequence motif of approximately 45 amino acid residues that are found in diverse proteins involved in the ubiquitin/proteasome pathway, DNA excision-repair, and cell signalling via protein kinases []. HHR23A, the human homologue of yeast Rad23A is a nucleotide excision-repair protein that contains both an internal and a C-terminal UBA domain. The fold of the UBA domain consists of a compact three-helical bundle with a right-handed twist, and have a conserved hydrophobic surface patch for protein-protein interactions. UBA-like domains can be found in other proteins as well, such as the TS-N domain in the elongation factor Ts (EF-Ts), which catalyses the recycling of the GTPase EF-Tu required for the binding of aminoacyl-tRNA top the ribosomal A site []; and the C-terminal domain of TAP/NXF1, which functions in nuclear export through the interaction of its UBA-like domain with FG nucleoporins []. Short Name:  UBA-like

4 Child Features

DB identifier Type Name
IPR015940 Domain Ubiquitin-associated domain
IPR015368 Domain Ubiquitin-conjugating enzyme, C-terminal fungi
IPR005637 Domain TAP C-terminal (TAP-C) domain
IPR015228 Domain Ubiquitin-associated domain, SWA2-type

2 Contains

DB identifier Type Name
IPR003892 Domain Ubiquitin system component Cue
IPR018101 Conserved_site Translation elongation factor Ts, conserved site

1 Cross References

Identifier
SSF46934

2 Found Ins

DB identifier Type Name
IPR001816 Family Translation elongation factor EFTs/EF1B
IPR017346 Family UBX domain-containing protein 2/7

1 GO Annotation

GO Term Gene Name Organism
GO:0005515 IPR009060

0 Parent Features

1185 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
140420 D8QTW6 PAC:15406653 Selaginella moellendorffii 413  
164130 D8QMR0 PAC:15408085 Selaginella moellendorffii 492  
171198 D8RG44 PAC:15406719 Selaginella moellendorffii 536  
419654 D8S9L7 PAC:15411275 Selaginella moellendorffii 323  
443383 D8S0X6 PAC:15413120 Selaginella moellendorffii 409  
63572 D8QVC9 PAC:15422801 Selaginella moellendorffii 390  
76038 D8QRM1 PAC:15412647 Selaginella moellendorffii 349  
140411 D8QTV1 PAC:15406625 Selaginella moellendorffii 297  
236729 D8TCN6 PAC:15411351 Selaginella moellendorffii 243  
266783 D8R038 PAC:15410767 Selaginella moellendorffii 246  
411052 D8RGF7 PAC:15405510 Selaginella moellendorffii 459  
60716 D8QTN3 PAC:15415584 Selaginella moellendorffii 877  
73901 D8QQC3 PAC:15410708 Selaginella moellendorffii 556  
82644 D8R1C4 PAC:15412760 Selaginella moellendorffii 385  
86216 D8R6K7 PAC:15421213 Selaginella moellendorffii 779  
95808 D8RKQ5 PAC:15407724 Selaginella moellendorffii 195  
102471 D8RVN1 PAC:15406140 Selaginella moellendorffii 214  
403971 D8QT57 PAC:15411219 Selaginella moellendorffii 237  
405547 D8QYY0 PAC:15413993 Selaginella moellendorffii 506  
407736 D8R6L0 PAC:15421143 Selaginella moellendorffii 717  
438753 D8QZ59 PAC:15423355 Selaginella moellendorffii 822  
77427 D8QS60 PAC:15418601 Selaginella moellendorffii 367  
evm.model.supercontig_3.162 PAC:16416438 Carica papaya 217  
evm.model.supercontig_3.37 PAC:16416668 Carica papaya 223  
evm.model.supercontig_1.181 PAC:16404101 Carica papaya 274  
evm.model.supercontig_12.132 PAC:16406673 Carica papaya 793  
evm.model.supercontig_12.20 PAC:16406748 Carica papaya 803  
evm.model.supercontig_12.91 PAC:16406935 Carica papaya 409  
evm.model.supercontig_132.9 PAC:16408177 Carica papaya 362  
evm.model.supercontig_14.127 PAC:16408622 Carica papaya 522  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12079361
            11744709
            12581645