Protein Domain : IPR020472

Type:  Repeat Name:  G-protein beta WD-40 repeat
Description:  WD-40 repeats (also known as WD or beta-transducin repeats) are short ~40 amino acid motifs, often terminating in a Trp-Asp (W-D) dipeptide. WD40 repeats usually assume a 7-8 bladed beta-propeller fold, but proteins have been found with 4 to 16 repeated units, which also form a circularised beta-propeller structure. WD-repeat proteins are a large family found in all eukaryotes and are implicated in a variety of functions ranging from signal transduction and transcription regulation to cell cycle control and apoptosis. Repeated WD40 motifs act as a site for protein-protein interaction, and proteins containing WD40 repeats are known to serve as platforms for the assembly of protein complexes or mediators of transient interplay among other proteins. The specificity of the proteins is determined by the sequences outside the repeats themselves. Examples of such complexes are G proteins (beta subunit is a beta-propeller), TAFII transcription factor, and E3 ubiquitin ligase [, ]. In Arabidopsis spp., several WD40-containing proteins act as key regulators of plant-specific developmental events.This entry represents a region that spans the WD-40 repeats in members of the WD repeat G protein beta family. Short Name:  G-protein_beta_WD-40_rep

0 Child Features

0 Contains

1 Cross References

Identifier
PR00320

6 Found Ins

DB identifier Type Name
IPR016346 Family Guanine nucleotide-binding protein, beta subunit
IPR016453 Family Coatomer beta' subunit (COPB2)
IPR017399 Family WD repeat protein DCAF11/LEC14B
IPR016391 Family Coatomer alpha subunit
IPR017252 Family Dynein regulator LIS1
IPR017251 Family Apoptotic protease-activating factor 1

0 GO Annotation

0 Parent Features

16962 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
106210 D8S1J6 PAC:15416247 Selaginella moellendorffii 308  
109958 D8S6N9 PAC:15408016 Selaginella moellendorffii 317  
121554 D8SNS5 PAC:15418401 Selaginella moellendorffii 442  
134213 D8T8C5 PAC:15409638 Selaginella moellendorffii 406  
139346 D8QPW0 PAC:15402692 Selaginella moellendorffii 737  
157928 D8SSK2 PAC:15415923 Selaginella moellendorffii 320  
173029 D8RNT8 PAC:15411729 Selaginella moellendorffii 346  
230900 D8R525 PAC:15417580 Selaginella moellendorffii 1340  
233294 D8S7F5 PAC:15421115 Selaginella moellendorffii 408  
233900 D8SFJ6 PAC:15403891 Selaginella moellendorffii 309  
266832 D8R1U5 PAC:15411407 Selaginella moellendorffii 392  
269383 D8SYB1 PAC:15416400 Selaginella moellendorffii 323  
269750 D8T680 PAC:15419395 Selaginella moellendorffii 307  
3288 D8RE96 PAC:15411506 Selaginella moellendorffii 194  
442453 D8RTJ1 PAC:15410870 Selaginella moellendorffii 466  
53217 D8RQ99 PAC:15413334 Selaginella moellendorffii 406  
65096 D8QZS3 PAC:15402572 Selaginella moellendorffii 362  
77651 D8QTS3 PAC:15420182 Selaginella moellendorffii 1213  
78344 D8QW94 PAC:15420780 Selaginella moellendorffii 554  
79275 D8QW58 PAC:15422899 Selaginella moellendorffii 908  
79926 D8QWK8 PAC:15405880 Selaginella moellendorffii 467  
81344 D8QZK5 PAC:15407412 Selaginella moellendorffii 525  
90562 D8RD83 PAC:15413442 Selaginella moellendorffii 590  
118822 D8SKF3 PAC:15411603 Selaginella moellendorffii 1180  
133091 D8T6F1 PAC:15405299 Selaginella moellendorffii 486  
141846 D8QWL1 PAC:15412753 Selaginella moellendorffii 560  
142121 D8QYQ4 PAC:15410306 Selaginella moellendorffii 375  
169971 D8RBM7 PAC:15406660 Selaginella moellendorffii 312  
179772 D8SHI3 PAC:15412406 Selaginella moellendorffii 355  
268258 D8S7R6 PAC:15412692 Selaginella moellendorffii 511  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10322433
            11814058