GO Term : GO:0000165 MAPK cascade GO

Namespace:  biological_process Obsolete:  false
description  An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

63 Ontology Annotations

GO Term Gene Name Organism
GO:0000165
GO:0000165
GO:0000165 AT1G24260 Arabidopsis thaliana
GO:0000165 AT1G22130 Arabidopsis thaliana
GO:0000165 AT4G29810 Arabidopsis thaliana
GO:0000165 AT4G29810 Arabidopsis thaliana
GO:0000165 AT4G26070 Arabidopsis thaliana
GO:0000165 AT5G10140 Arabidopsis thaliana
GO:0000165 AT1G08720 Arabidopsis thaliana
GO:0000165 AT5G62165 Arabidopsis thaliana
GO:0000165 AT1G01530 Arabidopsis thaliana
GO:0000165 AT1G69120 Arabidopsis thaliana
GO:0000165 AT4G09960 Arabidopsis thaliana
GO:0000165 AT5G60910 Arabidopsis thaliana
GO:0000165 AT3G58780 Arabidopsis thaliana
GO:0000165 AT5G51870 Arabidopsis thaliana
GO:0000165 AT5G13790 Arabidopsis thaliana
GO:0000165 AT1G26310 Arabidopsis thaliana
GO:0000165 AT3G57230 Arabidopsis thaliana
GO:0000165 AT5G65070 Arabidopsis thaliana
GO:0000165 AT5G20240 Arabidopsis thaliana
GO:0000165 AT5G23260 Arabidopsis thaliana
GO:0000165 AT5G65050 Arabidopsis thaliana
GO:0000165 AT2G22540 Arabidopsis thaliana
GO:0000165 AT2G45660 Arabidopsis thaliana
GO:0000165 AT4G08500 Arabidopsis thaliana
GO:0000165 AT4G37940 Arabidopsis thaliana
GO:0000165 AT2G14210 Arabidopsis thaliana
GO:0000165 AT5G51860 Arabidopsis thaliana
GO:0000165 AT2G03710 Arabidopsis thaliana

36 Parents

Identifier Name Description
GO:0006468 protein phosphorylation The process of introducing a phosphate group on to a protein.
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0016310 phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0006796 phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0035556 intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0006464 cellular protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0044267 cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

197 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0000165 GO:0000161
is_a GO:0000165 GO:0000161
is_a GO:0023014 GO:0000165
is_a GO:0035556 GO:0000165
is_a GO:0007165 GO:0000165
is_a GO:0006464 GO:0000165
is_a GO:0043170 GO:0000165
is_a GO:0044710 GO:0000165
is_a GO:0065007 GO:0000165
is_a GO:0006468 GO:0000165
is_a GO:0044238 GO:0000165
is_a GO:0044237 GO:0000165
is_a GO:0044699 GO:0000165
part of GO:0050896 GO:0000165
part of GO:0008150 GO:0000165
part of GO:0044699 GO:0000165
part of GO:0009987 GO:0000165
part of GO:0044700 GO:0000165
part of GO:0023052 GO:0000165
is_a GO:0008152 GO:0000165
is_a GO:0050789 GO:0000165
is_a GO:0008150 GO:0000165
is_a GO:0019538 GO:0000165
is_a GO:0071704 GO:0000165
is_a GO:0006796 GO:0000165
part of GO:0007154 GO:0000165
part of GO:0044763 GO:0000165
is_a GO:0006793 GO:0000165
is_a GO:0009987 GO:0000165
occurs in GO:0005575 GO:0000165

9 Synonyms

Name Type
MAPKKK cascade during sporulation synonym
MAPK signalling synonym
MAPK signaling synonym
mitogen-activated protein kinase cascade synonym
MAPKKK cascade synonym
MAP kinase cascade synonym
ERK/MAPK cascade synonym
MAPK signal transduction synonym
MAP kinase kinase kinase cascade synonym