Protein Domain : IPR017184

Type:  Family Name:  Serine/threonine-protein kinase Unc-51
Description:  This entry represents serine/threonine-protein kinases () such as Unc-51 from Caenorhabditis elegans. Unc-51 is important for axonal elongation and axonal guidance []. It is required for either the maintenance of axons (membrane turnover) or for an unknown neuronal function. C elegans worms lacking Unc-51 exhibit various abnormalities in axonal elongation and axonal structures. Unc-51 could also help control cell size along with Bec-1, as mutations in their corresponding genes results in a reduction in small body size without affecting cell number []. Short Name:  Ser/Thr_kinase_Unc51

0 Child Features

5 Contains

DB identifier Type Name
IPR000719 Domain Protein kinase domain
IPR011009 Domain Protein kinase-like domain
IPR002290 Domain Serine/threonine/dual specificity protein kinase, catalytic domain
IPR017441 Binding_site Protein kinase, ATP binding site
IPR008271 Active_site Serine/threonine-protein kinase, active site

2 Cross Referencess

Identifier
PTHR24348:SF2
PIRSF037369

0 Found In

1 GO Annotation

GO Term Gene Name Organism
GO:0004672 IPR017184

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16887826
            17890369