Protein Domain : IPR015807

Type:  Family Name:  Histidine-tRNA ligase
Description:  Histidine-tRNA ligase (also known as histidyl-tRNA synthetase) () is an alpha2 dimer that belongs to class IIa. Every completed genome includes a histidine-tRNA ligase. Apparent second copies from Bacillus subtilis, Synechocystis sp.(strain PCC 6803), and Aquifex aeolicusare slightly shorter, more closely related to each other than to other hisS proteins, and not demonstrated to act as histidine-tRNA ligases (see ). Theregulatory protein kinase GCN2 of Saccharomyces cerevisiae(YDR283c), and related proteins from other species designated eIF-2 alpha kinase, have a domain closely related to histidine-tRNA ligase that may serve to detect and respond to uncharged tRNA(his), an indicator of amino acid starvation, but these regulatory proteins are not orthologous. Short Name:  His-tRNA-ligase

0 Child Features

3 Contains

DB identifier Type Name
IPR004154 Domain Anticodon-binding
IPR006195 Domain Aminoacyl-tRNA synthetase, class II
IPR002314 Domain Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)

2 Cross Referencess


0 Found In

3 GO Annotations

GO Term Gene Name Organism
GO:0004821 IPR015807
GO:0005524 IPR015807
GO:0006427 IPR015807

1 Parent Features

DB identifier Type Name
IPR004516 Family Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit

234 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
122255 D8SPU2 PAC:15419074 Selaginella moellendorffii 423  
419303 D8S8H4 PAC:15408771 Selaginella moellendorffii 1665  
evm.model.supercontig_1431.2 PAC:16409022 Carica papaya 778  
29757.m000724 B9SHN6 PAC:16807998 Ricinus communis 886  
30078.m002290 B9S0H3 PAC:16817401 Ricinus communis 503  
Cucsa.088550.1 PAC:16957023 Cucumis sativus 879  
Cucsa.124750.1 PAC:16961763 Cucumis sativus 507  
GSVIVT01025735001 PAC:17833670 Vitis vinifera 404  
orange1.1g011527m PAC:18099159 Citrus sinensis 484  
orange1.1g003041m PAC:18129880 Citrus sinensis 854  
AT3G02760.1 F4IYF8 PAC:19664037 Arabidopsis thaliana 883  
AT3G46100.1 O82413 PAC:19660507 Arabidopsis thaliana 486  
Thhalv10020033m V4MBI7 PAC:20183209 Eutrema salsugineum 876  
Thhalv10013386m V4NC95 PAC:20206523 Eutrema salsugineum 488  
Ciclev10018820m V4TNC4 PAC:20807070 Citrus clementina 866  
Carubv10012946m R0I0J0 PAC:20900440 Capsella rubella 886  
Carubv10017103m R0FN33 PAC:20886673 Capsella rubella 489  
MDP0000711998 PAC:22665785 Malus domestica 806  
MDP0000182486 PAC:22632536 Malus domestica 433  
Lus10041073 PAC:23179604 Linum usitatissimum 875  
Lus10014422 PAC:23143670 Linum usitatissimum 499  
Lus10023925 PAC:23160742 Linum usitatissimum 499  
Lus10030341 PAC:23153141 Linum usitatissimum 875  
Potri.019G071400.1 PAC:27025986 Populus trichocarpa 885  
Potri.006G124400.1 U5G705 PAC:27004257 Populus trichocarpa 507  
Potri.019G071400.2 B9IQ90 PAC:27025985 Populus trichocarpa 885  
Potri.006G124400.2 U5GAD6 PAC:27004258 Populus trichocarpa 506  
Gorai.002G161900.1 A0A0D2Q7C5 PAC:26793930 Gossypium raimondii 504  
Gorai.004G262600.1 A0A0D2RB23 PAC:26771776 Gossypium raimondii 741  
mrna31205.1-v1.0-hybrid PAC:27262892 Fragaria vesca 878  

0 Publications