Protein Domain : IPR025304

Type:  Domain Name:  ALIX V-shaped domain
Description:  The binding of the LYPxL motif of late HIV p6Gag and EIAV p9Gag to this domain is necessary for viral budding. In ALIX, a component of the ESCRT pathway, this domain is central between an N-terminal Bro1 domain () and a C-terminal proline-rich domain. The ALIX central domain is formed by two three-helix bundles disposed in a V shape [, ]. Retroviruses thus used this domain to hijack the ESCRT system of the cell []. Short Name:  ALIX_V_dom

0 Child Features

0 Contains

1 Cross References

Identifier
PF13949

0 Found In

1 GO Annotation

GO Term Gene Name Organism
GO:0005515 IPR025304

0 Parent Features

167 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
102692 D8RVD3 PAC:15407659 Selaginella moellendorffii 867  
evm.model.supercontig_65.100 PAC:16424356 Carica papaya 868  
28565.m000327 B9T1V1 PAC:16801105 Ricinus communis 683  
Cucsa.280570.1 PAC:16974232 Cucumis sativus 568  
GSVIVT01011794001 PAC:17823567 Vitis vinifera 822  
orange1.1g002807m A0A067FF68 PAC:18095686 Citrus sinensis 878  
AT1G15130.1 F4HXZ1 PAC:19652619 Arabidopsis thaliana 846  
Thhalv10006787m V4L6B0 PAC:20186248 Eutrema salsugineum 847  
Ciclev10014287m PAC:20817123 Citrus clementina 822  
Carubv10008299m R0I3G1 PAC:20888753 Capsella rubella 845  
MDP0000321077 PAC:22641080 Malus domestica 857  
MDP0000503033 PAC:22626619 Malus domestica 182  
MDP0000219089 PAC:22625281 Malus domestica 884  
Lus10035265 PAC:23162585 Linum usitatissimum 909  
Lus10034634 PAC:23162815 Linum usitatissimum 996  
Potri.010G042800.1 PAC:26979305 Populus trichocarpa 268  
Potri.008G126900.1 B9HJ83 PAC:27040070 Populus trichocarpa 869  
Potri.008G126900.2 PAC:27040071 Populus trichocarpa 864  
Potri.010G116400.2 PAC:26979246 Populus trichocarpa 648  
Potri.010G116400.1 B9HWA0 PAC:26979245 Populus trichocarpa 861  
Gorai.005G192900.1 A0A0D2RI42 PAC:26805199 Gossypium raimondii 869  
mrna03621.1-v1.0-hybrid PAC:27252199 Fragaria vesca 702  
29959 I0YUJ6 PAC:27391987 Coccomyxa subellipsoidea C-169 713  
166396 C1MHK5 PAC:27345230 Micromonas pusilla CCMP1545 907  
105844 C1EAM1 PAC:27404475 Micromonas sp. RCC299 874  
39182 A4S5H0 PAC:27417156 Ostreococcus lucimarinus 856  
Thecc1EG009148t1 A0A061E6I6 PAC:27461289 Theobroma cacao 869  
Migut.E00398.1.p A0A022QQ27 PAC:28921778 Mimulus guttatus 873  
Araha.12397s0004.1.p PAC:28861312 Arabidopsis halleri 793  
Cagra.2238s0106.1.p PAC:28918218 Capsella grandiflora 845  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17350572
            17277784
            18066081