Protein Domain : IPR004041

Type:  Domain Name:  NAF domain
Description:  The NAF domain is a 24 amino acid domain that is found in a plant-specific subgroup of serine-threonine protein kinases (CIPKs), that interact with calcineurin B-like calcium sensor proteins (CBLs). Whereas the N-terminal part of CIPKs comprises a conserved catalytic domain typical of Ser-Thr kinases, the much less conserved C-terminal domain appears to be unique to this subgroup of kinases. The only exception is the NAF domain that forms an 'island of conservation' in this otherwise variable region. The NAF domain has been named after the prominent conserved amino acids Asn-Ala-Phe. It represents a minimum protein interaction module that is both necessary and sufficient to mediate the interaction with the CBL calcium sensor proteins [].The secondary structure of the NAF domain is currently not known, but secondary structure computation of the C-terminal region of Arabidopsis thalianaCBL-interacting protein kinase 1 revealed a long helical structure []. Short Name:  NAF_dom

0 Child Features

1 Contains

DB identifier Type Name
IPR018451 Domain NAF/FISL domain

1 Cross References


1 Found In

DB identifier Type Name
IPR020636 Family Calcium/calmodulin-dependent/calcium-dependent protein kinase

1 GO Annotation

GO Term Gene Name Organism
GO:0007165 IPR004041

0 Parent Features

1185 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
90416 C4P7R4 PAC:15412548 Selaginella moellendorffii 445  
234951 C4P7R5 PAC:15406962 Selaginella moellendorffii 442  
267186 C4P7R7 PAC:15409010 Selaginella moellendorffii 457  
135824 C4P7R6 PAC:15417184 Selaginella moellendorffii 432  
79434 C4P7R3 PAC:15402123 Selaginella moellendorffii 447  
evm.TU.contig_42087.1 PAC:16431691 Carica papaya 395  
evm.model.supercontig_103.105 PAC:16404892 Carica papaya 439  
evm.model.supercontig_127.24 PAC:16407386 Carica papaya 438  
evm.model.supercontig_144.3 PAC:16409047 Carica papaya 434  
evm.model.supercontig_146.21 PAC:16409109 Carica papaya 464  
evm.model.supercontig_177.4 PAC:16411125 Carica papaya 431  
evm.model.supercontig_2.321 PAC:16412699 Carica papaya 427  
evm.model.supercontig_2.325 PAC:16412703 Carica papaya 373  
evm.model.supercontig_46.10 PAC:16420378 Carica papaya 500  
evm.model.supercontig_58.10 PAC:16422941 Carica papaya 424  
evm.model.supercontig_7.83 PAC:16425248 Carica papaya 436  
evm.model.supercontig_7.84 PAC:16425249 Carica papaya 487  
evm.model.supercontig_86.32 PAC:16427584 Carica papaya 356  
evm.model.supercontig_95.74 PAC:16428918 Carica papaya 424  
27762.m000016 B9T8H6 PAC:16799129 Ricinus communis 446  
27766.m000155 B9T2E1 PAC:16799139 Ricinus communis 524  
27964.m000362 B9SVF5 PAC:16799649 Ricinus communis 346  
28297.m000110 B9T650 PAC:16800495 Ricinus communis 428  
28320.m001148 B9SET9 PAC:16800598 Ricinus communis 449  
29003.m000064 B9T6V8 PAC:16802139 Ricinus communis 432  
29588.m000851 B9SMT0 PAC:16803225 Ricinus communis 454  
29596.m000693 B9SMX5 PAC:16803390 Ricinus communis 446  
29599.m000169 B9T407 PAC:16803468 Ricinus communis 468  
29729.m002342 B9S4C5 PAC:16806991 Ricinus communis 457  
29844.m003184 B9RTG4 PAC:16810892 Ricinus communis 430  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID