Protein Domain : IPR027916

Type:  Domain Name:  Protein kinase-like domain, Apicomplexa
Description:  This entry represents the kinase-like domain found in the Rhoptry (ROP) pseudokinases from the intracellular parasite Toxoplasma gondii []. ROP2, ROP4 and ROP8 have a typical bi-lobed protein kinase fold, but lack catalytic activity [].ROP4 is localised to the rhoptries, secretory organelles at the apical end of the parasite, and is secreted from the parasite during host cell invasion []. ROP2 mediates an association between the parasitophorous vacuole (PV) and host cell mitochondria by inserting into the parasitophorous vacuole membrane (PVM) []. It plays important roles in rhoptry biogenesis, parasite invasion, and intracellular replication []. During host invasion, ROP2 is released from the vacuole membrane and becomes phosphorylated in the infected cells []. Short Name:  Kinase-like_dom_Apicomplexa

0 Child Features

0 Contains

1 Cross References

Identifier
PF14531

0 Found In

0 GO Annotation

1 Parent Features

DB identifier Type Name
IPR000719 Domain Protein kinase domain

1185 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
146897 D8RG80 PAC:15405067 Selaginella moellendorffii 409  
231127 PAC:15414521 Selaginella moellendorffii 530  
90416 C4P7R4 PAC:15412548 Selaginella moellendorffii 445  
92988 D8RFM9 PAC:15422220 Selaginella moellendorffii 354  
122526 PAC:15421159 Selaginella moellendorffii 323  
181752 D8SQ64 PAC:15418456 Selaginella moellendorffii 456  
234951 C4P7R5 PAC:15406962 Selaginella moellendorffii 442  
25384 D8R662 PAC:15420760 Selaginella moellendorffii 277  
271276 D8S3C7 PAC:15421658 Selaginella moellendorffii 364  
55695 D8RLQ2 PAC:15422250 Selaginella moellendorffii 262  
64580 D8RDF6 PAC:15403426 Selaginella moellendorffii 300  
76216 D8QSL1 PAC:15414207 Selaginella moellendorffii 312  
83225 D8R2Q2 PAC:15412597 Selaginella moellendorffii 317  
62369 D8R055 PAC:15418428 Selaginella moellendorffii 378  
63609 D8RE64 PAC:15423400 Selaginella moellendorffii 294  
80443 PAC:15405291 Selaginella moellendorffii 509  
90224 D8RCD7 PAC:15411058 Selaginella moellendorffii 333  
119400 D8SKL3 PAC:15411429 Selaginella moellendorffii 278  
135824 C4P7R6 PAC:15417184 Selaginella moellendorffii 432  
164743 D8QTZ0 PAC:15412823 Selaginella moellendorffii 267  
164119 D8QMQ0 PAC:15408038 Selaginella moellendorffii 543  
164063 D8QMJ5 PAC:15407392 Selaginella moellendorffii 489  
233667 D8SCV6 PAC:15401861 Selaginella moellendorffii 499  
24657 PAC:15420081 Selaginella moellendorffii 330  
79434 C4P7R3 PAC:15402123 Selaginella moellendorffii 447  
99940 D8RR03 PAC:15420380 Selaginella moellendorffii 310  
129451 D8T0Y7 PAC:15418710 Selaginella moellendorffii 289  
89070 D8RB45 PAC:15406334 Selaginella moellendorffii 756  
evm.TU.contig_29430.1 PAC:16429705 Carica papaya 470  
evm.TU.contig_42087.1 PAC:16431691 Carica papaya 395  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15470260
            19197235
            11448993
            12711703
            23742205