Protein Domain : IPR013126

Type:  Family Name:  Heat shock protein 70 family
Description:  Heat shock proteins, Hsp70 chaperones help to fold many proteins. Hsp70 assisted folding involves repeated cycles of substrate binding and release. Hsp70 activity is ATP dependent. Hsp70 proteins are made up of two regions: the amino terminus is the ATPase domain and the carboxyl terminus is the substrate binding region [].Hsp70 proteins have an average molecular weight of 70 kDa [, , ]. In most species, there are many proteins that belong to the Hsp70 family. Some of these are only expressed under stress conditions (strictly inducible), while some are present in cells under normal growth conditions and are not heat-inducible (constitutive or cognate) [, ]. Hsp70 proteins can be found in different cellular compartments(nuclear, cytosolic, mitochondrial, endoplasmic reticulum, for example).This entry represents the Hsp70 family, and includes chaperone protein DnaK and luminal-binding proteins. Short Name:  Hsp_70_fam

2 Child Features

DB identifier Type Name
IPR012725 Family Chaperone DnaK
IPR010236 Family ISC system FeS cluster assembly, HscA chaperone

1 Contains

DB identifier Type Name
IPR018181 Conserved_site Heat shock protein 70, conserved site

2 Cross Referencess

Identifier
PF00012
PR00301

0 Found In

0 GO Annotation

0 Parent Features

1185 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
443120 D8RYR3 PAC:15411431 Selaginella moellendorffii 655  
109750 D8S696 PAC:15406533 Selaginella moellendorffii 779  
12397 D8S2Q1 PAC:15404715 Selaginella moellendorffii 368  
232884 D8S0Z2 PAC:15422756 Selaginella moellendorffii 589  
412732 D8RLA8 PAC:15413923 Selaginella moellendorffii 654  
102691 D8RVG4 PAC:15407657 Selaginella moellendorffii 862  
230659 D8R398 PAC:15415474 Selaginella moellendorffii 657  
168287 D8R6D5 PAC:15420766 Selaginella moellendorffii 636  
37171 D8SSZ3 PAC:15409947 Selaginella moellendorffii 53  
440676 D8RDG8 PAC:15406500 Selaginella moellendorffii 743  
440900 D8RF84 PAC:15408617 Selaginella moellendorffii 660  
446858 D8SUY5 PAC:15403169 Selaginella moellendorffii 655  
412733 D8RLA9 PAC:15413924 Selaginella moellendorffii 155  
414734 D8RTS1 PAC:15419661 Selaginella moellendorffii 1382  
443126 D8RYS9 PAC:15411435 Selaginella moellendorffii 653  
96333 D8RLB2 PAC:15406910 Selaginella moellendorffii 378  
104343 D8RY91 PAC:15411268 Selaginella moellendorffii 107  
267815 D8RV35 PAC:15414315 Selaginella moellendorffii 660  
440382 D8RBE2 PAC:15404181 Selaginella moellendorffii 657  
416857 D8S0M0 PAC:15403871 Selaginella moellendorffii 982  
evm.TU.contig_34651.1 PAC:16430487 Carica papaya 290  
evm.TU.contig_34651.2 PAC:16430488 Carica papaya 132  
evm.model.supercontig_1.398 PAC:16404341 Carica papaya 648  
evm.model.supercontig_113.35 PAC:16406045 Carica papaya 712  
evm.model.supercontig_15.10 PAC:16409311 Carica papaya 665  
evm.model.supercontig_152.1 PAC:16409591 Carica papaya 797  
evm.model.supercontig_20.39 PAC:16413063 Carica papaya 680  
evm.model.supercontig_260.3 PAC:16415348 Carica papaya 654  
evm.model.supercontig_29.171 PAC:16416201 Carica papaya 722  
evm.model.supercontig_46.176 PAC:16420462 Carica papaya 651  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2686623
            2944601
            9476895
            2841196
            3282176
            2143562