Protein Domain : IPR020683

Type:  Domain Name:  Ankyrin repeat-containing domain
Description:  This entry represents the ankyrin repeat-containing domain. These domains contain multiple repeats of a beta(2)-alpha(2) motif. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes. The few known examples from prokaryotes and viruses may be the result of horizontal gene transfers []. The repeat has been found in proteins of diverse function such as transcriptional initiators, cell-cycle regulators, cytoskeletal, ion transporters and signal transducers. The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [, , , ]. Each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90oangle. The repeats stack together to form an L-shaped structure [, ]. Short Name:  Ankyrin_rpt-contain_dom

0 Child Features

1 Contains

DB identifier Type Name
IPR002110 Repeat Ankyrin repeat

5 Cross Referencess


18 Found Ins

DB identifier Type Name
IPR020676 Family Death-associated protein kinase 1
IPR008297 Family Notch
IPR017408 Family Arginine N-methyltransferase 2
IPR017417 Family Protein phosphatase 1, regulatory subunit 16A/B
IPR017362 Family DNA-binding, RFXANK
IPR017401 Family Protein phosphatase 1 regulatory subunit 12A/B, chordates
IPR022336 Family Neurogenic locus Notch 2
IPR022355 Family Neurogenic locus Notch 4
IPR022331 Family Neurogenic locus Notch 3
IPR005463 Family Transient receptor potential channel, canonical 7
IPR022362 Family Neurogenic locus Notch 1
IPR005460 Family Transient receptor potential channel, canonical 4
IPR005457 Family Transient receptor potential channel, canonical 1
IPR004729 Family Transient receptor potential channel
IPR008348 Family Transient receptor potential channel, vanilloid 4
IPR008347 Family Transient receptor potential channel, vanilloid 1-4
IPR008345 Family Transient receptor potential channel, vanilloid 6
IPR008344 Family Transient receptor potential cation channel subfamily V member 5/6

0 GO Annotation

0 Parent Features

21045 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
444080 D8S6B3 PAC:15413764 Selaginella moellendorffii 156  
105905 D8S0G7 PAC:15418654 Selaginella moellendorffii 395  
106391 D8S1Q0 PAC:15417178 Selaginella moellendorffii 625  
114584 D8SD81 PAC:15420039 Selaginella moellendorffii 336  
124258 D8ST20 PAC:15402494 Selaginella moellendorffii 95  
132360 PAC:15404558 Selaginella moellendorffii 725  
163545 D8QPF7 PAC:15408282 Selaginella moellendorffii 1051  
169694 D8RAP7 PAC:15404357 Selaginella moellendorffii 654  
3903 D8R6Y0 PAC:15416614 Selaginella moellendorffii 271  
403038 D8QNV1 PAC:15404080 Selaginella moellendorffii 409  
408628 D8R9F6 PAC:15423281 Selaginella moellendorffii 341  
413320 D8RP30 PAC:15413711 Selaginella moellendorffii 969  
422895 D8SJW6 PAC:15421809 Selaginella moellendorffii 511  
440857 D8REX8 PAC:15407927 Selaginella moellendorffii 387  
4649 D8QR34 PAC:15417358 Selaginella moellendorffii 140  
50132 D8S5Z7 PAC:15403700 Selaginella moellendorffii 908  
5251 D8S9U6 PAC:15417237 Selaginella moellendorffii 194  
62212 D8QRK0 PAC:15417551 Selaginella moellendorffii 591  
110129 D8S6B5 PAC:15405059 Selaginella moellendorffii 516  
122416 D8SQD8 PAC:15420480 Selaginella moellendorffii 570  
141633 D8QXZ3 PAC:15411241 Selaginella moellendorffii 447  
173073 D8RP22 PAC:15411848 Selaginella moellendorffii 307  
232336 PAC:15418944 Selaginella moellendorffii 750  
167008 D8R0R2 PAC:15416174 Selaginella moellendorffii 161  
228083 D8RLX4 PAC:15404632 Selaginella moellendorffii 162  
418698 D8S6V6 PAC:15408328 Selaginella moellendorffii 412  
402887 D8QNC8 PAC:15407369 Selaginella moellendorffii 198  
418760 D8S6B2 PAC:15409065 Selaginella moellendorffii 316  
440808 D8REJ0 PAC:15407827 Selaginella moellendorffii 302  
441667 D8RLU7 PAC:15409450 Selaginella moellendorffii 982  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID